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Ritalin Price | What is Methylphenidate

Methylphenidate hydrochloride is the reference molecule in the treatment of attention deficit hyperactivity disorder; it is better known as Ritalin.

The relationship between the mode of action and the therapeutic effect in attention deficit hyperactivity disorder (ADHD) is unknown. Methylphenidate is thought to block the reuptake of norepinephrine and dopamine at the level of presynaptic neurons and increase the release of these monoamines into extraneuronal space.

Methylphenidate is used in the management of:

• narcolepsies;
• Attention deficit hyperactivity disorder (ADHD) in children.

This molecule, discovered in 1937, was patented in 1954 and then marketed in the United States starting in the 1960s. It was only marketed in France in 1995. It is the only molecule currently available in France.

Methylphenidate owes its sulfurous reputation to the fact that it’s a molecule similar to amphetamine and to the annoying trend of certain people having to make amalgams. Indeed, although this molecule is classified as a drug, calling it a drug that’s evolving into a hard drug is insane.

Ritalin online | What does Ritalin do?

Buying Ritalin is a powerful psychostimulant. Paradoxically, and without understanding its mechanism of action, it’s possible to regulate the pathological hyperactivity of certain children.

It is used to treat attention deficit hyperactivity disorder in children over 6 years old and in adults. This specific condition, which should not be confused with a somewhat “tonic” personality, is generally associated with a lack of attention, an inability to concentrate, emotional instability, impulsiveness, and hyperactivity (the child can’t stay in their place).

The diagnosis must be made by a neurologist, psychiatrist, or pediatrician based on medical and psychological criteria and assessing the academic and family impact of the affection. This set of conditions can also be observed in children who are depressed, psychotic, or exposed to a traumatic environment. In these cases, specific measures are taken to address these causes of psychological disorders before prescribing Ritalin.

The tablets are also used in the treatment of narcolepsy in adults and children over 6 years of age, in case of ineffectiveness of  modafinil  treatment.

Studying Ritalin

Ritalin treatment is not prescribed for life; in the Netherlands, it is prescribed for an average of 3 years and 6 months. It is not a curative treatment; we do not cure ADD/H, but in practice, we see that treated children develop better compensatory capacities for their attention deficit disorder.

Numerous studies demonstrate the safety of methylphenidate, even at doses 30 times higher than those used in Belgium. Studies conducted on methylphenidate in children emphasize the absence of serious side effects, the most common of which are decreased appetite, headache, and abdominal pain.

Methylphenidate experiences

Clinically the positive effects are observed quickly, in our experience we often report:

• Improving attention skills in the classroom and outside the classroom;
• These children communicate more with their family;
• less effort to get to work;
• decrease in impulsiveness;
• Improving academic results (provided you work, otherwise don’t dream…);
• Improved long-term self-confidence.

Effects of methylphenidate (Ritalin) on the brain

Methylphenidate acts as a reuptake inhibitor of dopamine and norepinephrine at the cerebral level, meaning it increases their speed in the brain. Not only does it increase their presence, but also their affinity for receptors, resulting in an improvement in signal strength and quality.

This is a summary of what we’ve learned from the research conducted; brain function is much more complex than that, and it’s a safe bet that many receptors and other molecules are involved.
Dopamine supplements are therefore a nameless nonsense.

Its use is justified by many clinical studies that have proven its effectiveness.

Studies have shown in MRI that certain structural brain abnormalities in these young people are normalized thanks to methylphenidate. The increase in functional imaging has allowed further observation of beneficial changes in children treated with Ritalin (improvement, even normalization, of brain activity during attention and resting tasks).

Ritalin methylphenidate side effects

There’s no such thing as a perfect treatment; prescribing a medication often involves a reverse of the coin. A positive aspect of methylphenidate is that we have about sixty years of perspective and are aware of the adverse effects. But be careful, as I also repeat to my patients: on the one hand, we have the visible effects, and on the other, the invisible effects, which we can discover later.

The most common side effects associated with taking Ritalin methylphenidate are:

• Decreased appetite: frequently affects many patients who
• monitor drug treatment;
• Headaches: They are common at the beginning of treatment and every
• adjustment of the treatment dosage;
• Abdominal pain: these are also common at the beginning of treatment;
• Difficulty falling asleep or even insomnia: this side effect is relatively common with long-term release medications. Sometimes, on the contrary, the difficulty falling asleep that was present before treatment disappears.

Treatment monitoring includes: weight, height, pulse and blood pressure.

Note that recent studies highlight the risk of poorer bone mineralization in adults treated with Ritalin during childhood. I recommend my patients a diet rich in dairy products and vitamin D supplements (which help repair calcium) during the winter months, which are from September to May.

Ritalin contraindications

Methylphenidate should not be used in the following cases:

• closed angle glaucoma;
• Pheochromocytoma;
• hyperthyroidism;
• Psychosis, anorexia, manifestations of anxiety, severe depression;
• bipolar disorder poorly controlled by treatment;
• Heart conditions (severe high blood pressure, heart failure, angina, myocardial infarction, heart rate disorders, etc.);
• already before the vascular disorder, cerebral aneurysm, stroke;
• In conjunction with a non-selective MAO and during the 14 days of his stop.

Ritalin Methylphenidate dosage

The tablets should be taken with a glass of water.

The capsules should be swallowed once a day in the morning. They can be opened and their contents mixed, without being crushed, with a compote or yogurt.

Usual dosage

Attention deficit hyperactivity disorder

• Children over 6 years:  Treatment is generally initiated with 1/2 tablet in the morning and afternoon. The dosage can be gradually increased each week to a maximum dose of 60 mg. Avoid giving the medication in the evening as much as possible: risk of nervousness and insomnia.
• Adults:  Only sustained-release capsules can be used for this indication. The dosage is strictly individualized. The ELL dose is increased gradually and should not exceed 80 mg per day.

Narcolepsy

• Adults:  1 tablet, 2 or 3 times a day, the last intake taking place at bedtime.
• Child over 6 years:  1/2 to 1 tablet, 2 or 3 times a day.